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Combining diverse expertise – Imperial College Network of Excellence in Malaria

By Dr Aubrey Cunnington, Clinical Senior Lecturer in Paediatric Infectious Diseases and Dr Jake BaumReader in Parasite Cell Biology, Faculty of Natural SciencesDepartment of Life Sciences, Imperial College London 

WHO/S. Hollyman

World Malaria Day is a good time to reflect on successes in the fight against malaria and the enormous challenges that still lie ahead. Malaria is a mosquito-transmitted parasitic disease, which causes illness ranging from severe flu-like symptoms to coma and death. Those at greatest risk are small children and pregnant women. It is an ancient enemy of mankind, and has exerted a powerful influence on our evolution. Malaria is a cunning foe, the parasites stay one step ahead of our immune systems allowing repeated infections to occur and they have a great capacity to develop resistance to antimalarial drugs.

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Malaria in 2017 – “It is too soon to be complacent”

By Professor Kathryn MaitlandProfessor of Tropical Paediatric Infectious Diseases, Director of Centre for African Research and Engagement, Imperial College London 

MosquitoApproximately 1200 African children are estimated to die from malaria every day, accounting for the vast majority of the global deaths from this disease. Over the past decade there has been an unprecedented increase in funding for malaria-control activities and vaccine development – the two major tools in ‘Roll back Malaria’ prevention and elimination programme. This has resulted in major scaling-up in the distribution of bed nets treated with long-lasting insecticides and public-private funding for late phase multi-site trials of the most promising anti-malaria vaccine candidate developed to date (RTS,S).

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SMILE – a smart vaccine cooling system for the last-mile journey in developing countries

By Kitty Liao and Abellona U of Ideabatic, IGHI’s 2017 Student Challenges Competition winners

IdeabaticEach year, there are two to three million children who die of a vaccine-preventable disease and there are 19.4 million who are unable to receive basic immunisation. One of the main reasons behind these figures is that the carrier boxes currently used to carry vaccines during the last miles of the delivery journey are incapable of sustaining the vaccines at the required temperature range for the entire duration of the journey. This is an urgent global health issue and Ideabatic is developing a solution called SMILE— a smart last-mile cooling and delivery system to address these problems. We presented Ideabatic at the IGHI’s Student Challenges Competition in March this year and won the first prize.

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Infectious Diseases Hub speaks to tuberculosis experts from CICH seminar

Last week IGHI’s Global Health Forum linked up with the Centre for International Child Health (CICH) for the first event in their bi-monthly seminar series focusing on the question, ‘Tuberculosis- why are we not winning the fight?’

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Engaging with a public engagement project: Understanding TB from the experiences of the ill

By Bianca Masuku, Eh!woza

Students on a shoot day, interviewing a local resident in the neighbourhood of Nkanini.

Eh!woza is an evolving public engagement project focused on two infectious diseases (HIV and TB) that continue to burden communities within South Africa. The initiative is based at the recently awarded Wellcome Centre for Infectious Disease Research in Africa, and the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town. Previously described on this blog, this piece provides insights into an anthropological investigation of the work of Eh!woza, as well as the personal and lived experiences of persons affected by TB throughout South African communities.

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Tuberculosis in England: How research at Imperial is supporting the national strategy

By Dr Luis C. Berrocal-Almanza, Research Associate- Epidemiologist and Dr Alice Halliday, Research Associate, Imperial College London

World TB Day on 24 March commemorates the announcement by Dr Robert Koch in 1882 of his discovery of Mycobacterium tuberculosis (Mtb) as the cause of tuberculosis (TB), a disease that still affects approximately 10 million people and causes 1.8 million death globally each year. The Royal Society of Medicine commemorates this day with an annual TB meeting to review the most relevant advances in clinical, public health and scientific aspects of TB, organised by Professor Ajit Lalvani of the National Heart & Lung Institute, Imperial College London.

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ActiveMiles – an intelligent food intake and energy expenditure mobile application

By Dr Daniele Ravi, Research Associate, Faculty of EngineeringDepartment of Computing, Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation

Obesity is a growing global health problem that has received increasing attention in recent years. It has been estimated that over 700 million people in the world are classified as obese. In the UK, the obese population has more than triple in the last 25 years.  Obesity has been identified as an escalating global epidemic health problem and is found to be associated with many chronic diseases, including type 2 diabetes, cardiovascular diseases and cancer. Although there is well-publicised guidance on recommended daily calories intake, very seldom people will comply with such guideline as recording of calorie intake is time consuming and inaccurate, as methods for dietary and daily activity assessments mostly rely on questionnaires or self-reporting.

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Is bariatric (weight-loss) surgery safe and effective in renal transplant patients?

By Emma Rose McGlone, RCS-funded research fellow, PhD student and bariatric surgery registrar, department of metabolic medicine, Hammersmith Hospital.
Author of ‘Is bariatric surgery in patients following renal transplantation safe and effective? A best evidence topic’ 

Many patients undergoing renal transplant are overweight or obese. This is not surprising given that the two most common causes of long-term renal failure in this country are type 2 diabetes and high blood pressure, conditions often associated with obesity. After transplant, many patients gain further weight: on average 8-14kg during the year after transplant. There are several reasons for this, including the immunosuppressant drugs, such as steroids, given to patients after transplant to prevent kidney rejection.

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Women in Surgery Sticking Together

By Saniya Mediratta, President of the ICSM Surgical Society

It seems strange to me, that when women have shattered the proverbial glass ceiling in innumerable fields, the statistics of women in surgery are still so low. At an astonishing 11.1%, the only heartening news is that it was once as low as 3% in 1991.

Why isn’t the field of surgery evolving with the current shift in workplace demographics? Why aren’t women choosing to pursue the seemingly impossible journey that is surgical training?

Why are so few of us women, studying medicine, not drawn to a career that inspires such awe, pride and prestige in the single word, “surgeon?” Is it because of distorted perceptions that see this plum role more suited to agentic males that are perceived to be assertive, able, task-orientated and competitive, as opposed to women that are often thought of as only nurturing, sensitive and communal?

Speaking to young female medics and doctors, many speak of concerns about the gruelling and intensive training, the impossibility of being able to maintain a work-life balance, or conversations about deskilling if time is taken out for child care, and the one that riles me most, the gender inequity and pay gap that still exists in the surgical field. Continue reading

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